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David Sanders is an Associate Professor of Biological Sciences at Purdue University.〔''Department Biological Sciences, Purdue University'', (), Web. 2 February 2010,〕 He grew up in Teaneck, New Jersey and then attended the Horace Mann School in Riverdale, NY. 〔http://www.jconline.com/article/20130714/OPINION03/307140008/Guest-column-When-school-loses-sight-mission〕 He received his Bachelor of Science degree from Yale College in Molecular Biophysics and Biochemistry.〔"David Sanders Lab, Bio" (), Web. 2 February 2010〕 He conducted his Ph.D. research in Biochemistry with Daniel E. Koshland, Jr., who was then editor of the journal Science, at the University of California at Berkeley. Sanders demonstrated that the response regulators in the two-component regulatory systems were phosphorylated on an aspartate residue and that they were protein phosphatases with a covalent intermediate.〔http://www.jbc.org/content/264/36/21770.full.pdf〕〔http://www.ncbi.nlm.nih.gov/pmc/articles/PMC206329/〕 ==Scientific career== He originated the idea of the "Molecule of the Year" feature in ''Science''. He was a Visiting Scientist at the University of California at San Francisco, and then a postdoctoral fellow at the Whitehead Institute for Biomedical Research, which is affiliated with M.I.T. It was there that he began his studies on the entry of viruses into cells with a focus on the inhibition of infection and applications to gene therapy. He joined the Markey Center for Structural Biology at Purdue University in 1995, where he is the leader of the Molecular Virology program 〔"Indy.com | Post: Schools waging the good fight against flu | Indianapolis, Indiana." Indy.com | Indianapolis, Indiana., (), Web. 2 February 2010〕 and also a member of the Cancer Center. He was the discoverer of a biochemical reaction, thiol-disulfide exchange, that leads to the entry of cancer-causing retroviruses into cells.〔http://www.springerlink.com/content/grxj7427006342x3/, (), Web. 2 February 2010〕〔"ScienceDirect - Drug Discovery Today : Ancient viruses in the fight against HIV." ScienceDirect - Home., (), Web. 2 February 2010.〕〔"Localization of the labile disulfide bond between SU and TM of the murine leukemia virus envelope protein complex to a highly conserved CWLC motif in SU that resembles the active-site sequence of thiol- disulfide exchange enzymes -- Pinter et al. 71 (10): 8073 --." The Journal of Virology., (), Web. 2 February 2010.〕 He also is the primary inventor on two U.S. patents on novel gene-therapy delivery techniques. His work on the Ebola virus led to his participation in the U.S. Defense Threat Reduction Agency's Biological Weapons Proliferation Prevention Program, a product of the Nunn-Lugar legislation.〔"Making a name by being himself." Evansville Courier & Press: Local Evansville, Indiana News Delivered Throughout the Day., (), Web. 2 February 2010.〕 His responsibilities included inspecting the Vector laboratory in Siberia, which was the site of biological-weapons development in the era of the Soviet Union. He has investigated the transmission of viruses from other animals, especially birds, to humans and has been invited to speak on ethics,〔"Student Pugwash conference at Purdue University. : Adventures in Ethics and Science." ScienceBlogs., (), Web. 2 February 2010.〕 biodefense, evolution, gene therapy, vaccination and influenza viruses in public forums including regular interviews on WIBC in Indianapolis,〔"Researchers Continue Learning About H1N1 | Indy's News Center - 93.1 WIBC Indianapolis - Live. Local. First." Indy's News Center - 93.1 WIBC Indianapolis - Live. Local. First., (), Web. 2 February 2010〕 He is a recipient of a National Science Foundation Career Award for his work on an enzyme that is involved in production of the greenhouse gas and potential energy source, methane 〔"DIR9." Nsf.gov - National Science Foundation - US National Science Foundation (NSF). , (). Web. 2 February 2010.〕 He is also an American Cancer Society Research Scholar. In 2003 he conducted his sabbatical research at the Weizmann Institute in Israel. Sanders has been a vocal critic of the ''Science'' article authored by Felisa Wolfe-Simon and Paul Davies in which the discovery of arsenic-based life is claimed.〔("The Alien Discovery that Wasn't" Odyssey magazine )〕 Sanders has argued that the original ''Science'' article on the arsenic bacteria should be retracted on the basis that the data in the paper were misrepresented in the article.〔http://retractionwatch.wordpress.com/2012/07/09/despite-refutation-science-arsenic-life-paper-deserves-retraction-scientist-argues〕〔http://www.periodicplayground.com/blog/bp/2013/02/guest-post-david-sanders-why-its-high-time-to-retract-arseniclife〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「David Sanders (biologist)」の詳細全文を読む スポンサード リンク
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